Pharmsteri™ II GHC PES

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Pharmsteri™ II GHC PES Liquid Capsule Filter


Product Overview

The Pharmsteri™ II GHC PES is a premium liquid filter from Entegris, specifically engineered to meet the stringent requirements of the pharmaceutical and biotechnology industries. Featuring a dual-layer asymmetric PES membrane and broad chemical compatibility, it delivers exceptional filtration performance and high reliability in sterile filtration processes.


Technical Specifications

Model Membrane Pore Size (µm) Membrane Structure Housing Material Gamma Sterilizable Operating pH Range
Pharmsteri™ II GHC 0.45 + 0.22 or 0.65 + 0.22 Dual-layer, asymmetric PES Gamma-stable Polypropylene Yes 1–14

Key Features

  • High Filtration Efficiency: Dual asymmetric PES membrane structure enhances flow rate and reduces pressure drop—ideal for filtering challenging liquid solutions.

  • Optimized Design: Specialized core and housing design minimizes hold-up volume, reducing product loss—especially important for high-value fluids.

  • Broad Chemical Compatibility: Effective across a wide pH range (1–14), suitable for use with acids, bases, and various process chemicals.

  • Sterile Filtration Standards: Complies with ASTM F838 for bacterial retention, ensuring microbial safety without compromising product quality.

  • Gamma Sterilizable: Compatible with single-use systems; can be sterilized by gamma irradiation for integration into sterile environments.


Benefits

  • Enhanced Process Efficiency: High flow and low differential pressure reduce filtration time and increase throughput.

  • Reduced Operational Costs: Low hold-up volume means less product waste, translating to lower overall processing costs.

  • Guaranteed Product Integrity: Sterile-grade filtration and chemical resistance preserve the purity and efficacy of final products.


Applications

  • Pharmaceutical Manufacturing: Sterile filtration of biologics, monoclonal antibodies (mAbs), and other pharmaceutical products.

  • Biotechnology Processes: Filtration of buffers, culture media, and other sensitive biological fluids.

  • Sterile Single-Use Systems: Integrated into disposable processing setups for high-purity, contamination-free operations.

 

 

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Reference link: https://www.entegris.com/shop/en/USD/products/liquid-filtration-and-purification/liquid-filters/Pharmsteri-II-GHC-PES-Liquid-Capsule-Filter/p/PharmsteriIIGHCPESLiquidCapsuleFilter?industry=

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